Development of glutamic acid decarboxylase immunoreactivity in the cat's lateral geniculate nucleus

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Glutamic acid decarboxylase-immunoreactive neurons and terminals in the lateral geniculate nucleus of the cat.

We have examined the distribution of neurons and terminals that are immunoreactive for glutamic acid decarboxylase (GAD), the synthesizing enzyme for the inhibitory neurotransmitter gamma-aminobutyric acid within the lateral geniculate nucleus of the cat. We estimate that GAD-positive neurons constitute approximately one-fourth of the neurons in all layers of the lateral geniculate nucleus and ...

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The lateral geniculate nucleus (LGN) is a huge embarrassment to visual neuroscientists. Virtually all the visual information that leaves the retina to be analysed in the visual cortex is relayed through synapses in this nucleus. It is a dogma of neurophysiology that the cost imposed by putting a synapse in any pathway must be repaid by some benefit in terms of processing. Unfortunately it is no...

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Coexistence of glutamic acid decarboxylase- and somatostatin-like immunoreactivity in neurons of the feline nucleus reticularis thalami.

The presence of somatostatin-like (SOM) immunoreactivity within GABAergic neurons of the nucleus reticularis thalami (NRT) was demonstrated by immunocytochemical methods in the cat using a two-color, double immunoperoxidase method with antisera raised in different species. GABAergic neurons were identified by means of a sheep antiserum to glutamic acid decarboxylase, the biosynthetic enzyme for...

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The multifunctional lateral geniculate nucleus.

Providing the critical link between the retina and visual cortex, the well-studied lateral geniculate nucleus (LGN) has stood out as a structure in search of a function exceeding the mundane 'relay'. For many mammals, it is structurally impressive: Exquisite lamination, sophisticated microcircuits, and blending of multiple inputs suggest some fundamental transform. This impression is bolstered ...

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ژورنال

عنوان ژورنال: The Journal of Neuroscience

سال: 1986

ISSN: 0270-6474,1529-2401

DOI: 10.1523/jneurosci.06-05-01410.1986